By Pierfausto Seneci
This publication is a neurochemistry-based significant other for Protein Misfolding and Neurodegenerative ailments: Molecular Targets, an Elsevier name via an identical writer publishing in December 2014. whereas the 1st e-book specializes in biology and molecular objectives, this better half ebook describes how those objectives are regulated through small molecules and disease-modifying compounds. The e-book starts off with a short advent to how key proteins develop into dysfunctional, and every next bankruptcy describes significant affliction mechanisms in Alzheimer’s and different tauopathies. houses and improvement prestige of those molecular goals and illness mechanisms are completely defined, as are small molecule effectors of autophagy and dis-aggregating brokers.
- Written to supply finished assurance of neurodegenerative disease-modifying compounds
- Provides discipline-specific chapters that hide medicinal chemistry and scientific applications
- Provides an summary of greater than 2 hundred chemical sessions and lead compounds, performing on chosen molecular pursuits which are of relevance to any neurodegenerative disorder
- Coverage of misfolding ailments, chaperone proteins, ubiquitination and autophagy/oncology makes this e-book appropriate for structural neurochemists, chemists, biologists, non-CNS scientists, and scientists attracted to drug discovery
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Chemical Modulators of Protein Misfolding and Neurodegenerative Disease by Pierfausto Seneci