Download Absorption and Drug Development: Solubility, Permeability, by Alex Avdeef PDF

By Alex Avdeef

Explains how one can practice and examine the result of the most recent physicochemical methods

With this e-book as their advisor, readers have entry to the entire present info had to completely examine and thoroughly be certain a compound's pharmaceutical homes and their results on drug absorption. The booklet emphasizes oral absorption, explaining all of the physicochemical equipment used this day to investigate drug applicants. furthermore, the writer offers specialist counsel to assist readers research the result of their reviews so one can choose the main promising drug candidates.

This Second Edition has been completely up-to-date and revised, incorporating all of the most up-to-date learn findings, equipment, and assets, including:

  • Descriptions and functions of recent PAMPA types, drawing on greater than thirty papers released through the author's learn group

  • Two new chapters reading permeability and Caco-2/MDCK and permeability and the blood-brain barrier

  • Expanded details and strategies to help pKa determination

  • New examples explaining the remedy of essentially insoluble attempt compounds

  • Additional case experiences demonstrating using the newest physicochemical techniques

  • New, revised, and accelerated database tables in the course of the book

Well over 2 hundred drawings support readers higher comprehend tricky suggestions and supply a visible advisor to complicated strategies. moreover, over 800 references function a gateway to the first literature within the box, facilitating additional examine into the entire subject matters lined within the book.

This Second Edition is suggested as a reference for researchers in pharmaceutical R&D in addition to in agrochemical, environmental, and different similar parts of analysis. it's also steered as a supplemental textual content for graduate classes in pharmaceutics.

Show description

Read or Download Absorption and Drug Development: Solubility, Permeability, and Charge State PDF

Best industrial & technical chemistry books

Zero Emissions Power Cycles

Targeting fossil-fueled, nonpolluting strength iteration structures, 0 Emissions energy Cycles provides replacement options to the critical emissions difficulties of strength vegetation. besides an outline of latest thermodynamic cycles and the result of computational analyses, this quantity presents sleek analytical instruments and equations to guage exergy and introduce "currentology".

Nanocoatings and Ultra-Thin Films: Technologies and Applications (Woodhead Publishing Series in Metals and Surface Engineering)

Coatings are used for a variety of purposes, from anti-fogging coatings for glass via to corrosion keep an eye on within the aerospace and car industries. Nanocoatings and ultra-thin motion pictures offers an updated evaluation of the basics, tactics of deposition, characterisation and functions of nanocoatings.

Electrochemically Enabled Sustainability: Devices, Materials and Mechanisms for Energy Conversion

Electrochemically Enabled Sustainability: units, fabrics and Mechanisms for strength Conversion covers subject matters on the topic of present examine in electrochemical energy assets, highlighting the various most recent strategies in electrochemical conversion for sustainability. The ebook examines the newest and cutting edge applied sciences hired in battery and gas mobilephone know-how.

Chemische Reaktionstechnik (Chemie in der Praxis) (German Edition)

Dieses Lehrbuch wendet sich primär an Studierende der Chemie, des Chemieingenieurwesens und der Verfahrenstechnik an Fachhochschulen und im universitären Bereich. Es soll darüber hinaus Ingenieuren und Fachkräften, denen reaktionstechnische Aufgabenstellungen in der Berufstätigkeit begegnen, die erforderlichen Hilfsmittel zu deren Lösung aufzeigen und eine Ergänzung ihrer Fachkenntnisse ermöglichen.

Extra info for Absorption and Drug Development: Solubility, Permeability, and Charge State

Example text

Download PDF sample

Absorption and Drug Development: Solubility, Permeability, and Charge State by Alex Avdeef


by Ronald
4.1

Rated 4.72 of 5 – based on 44 votes